Set on bluffs above the muddy, flood-prone Mississippi River, the city has long been a crossroads of water-borne and land transportation in the heartland of America.
These false-color images compare conditions along the Mississippi and Yazoo Rivers around Vicksburg in June 2011, during heavy flooding, and three years earlier.
Coming off of the extreme floods of 2011, the river was approaching historic lows in the summer of 2012 near Memphis and along much of its lower reaches.